The Noonday Demon “takes readers on a journey of incomparable range and resonance” (O, The Oprah Magazine), revealing the subtle complexities and sheer agony of depression. Andrew Solomon interviews patients, doctors and scientists, policy makers and politicians, drug designers and philosophers to describe the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has on various demographic populations—around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.