Presents a mix of interrelated stories: a Mexican policeman finds himself and his partner caught in an often deadly web of corruption; a pair of DEA agents work undercover in a sordid and dangerous part of San Diego; a wealthy drug baron living in upscale, suburban America is arrested and learns how quickly his unknowing and pampered wife takes over his business; and the U.S. President's new drug czar must deal with his increasingly drug-addicted teenage daughter.