After escaping from the asylum in Baltimore, Dr. Hannibal Lector, moves to Florence, Italy where he has become one of the curators of the Palazzo Vecchio. His cover is broken when a cop, for money, turns Dr. Lecter over to his old patient, Mason Verger. FBI agent Clarice Starling finds out about Mason's evil plot to feed Dr. Lecter to a bunch of man-eating hogs and will do anything to make sure that Mason doesn't succeed.