It's 1957 when Indiana Jones' latest expedition is crashed by a ruthless squad of Russian soldiers. The menacing Reds drag an unwilling Jones along as they brazenly invade American soil, massacre U.S. soldiers, and plunder a top-secret government warehouse. After being fired by his university and branded as a suspected spy Jones wants to retire, but a colleague's kidnapping leads Jones into the depths of the Amazon jungle on a desperate rescue mission.