A small Colorado town becomes the battleground between two of the deadliest extra-terrestrial lifeforms - the Alien and the Predator. When a Predator scout ship crash-lands in the hills outside the town, Alien facehuggers are released in the crash. Also released is a hybrid Alien/Predator. A man and his son hunting in the forest near the crash site soon become the first victims of the facehuggers. A Predator receives data about the crash on his home planet and he comes to Earth. One at a time, the inhabitants of the town become targets of the Aliens and the Predator. The National Guard is called in, but they are unable to stop the deadly creatures. A plan is set in motion to destroy the town with a nuclear device.