What makes Isaiah so unique? First, his fur is as blue as the sky, and he can read and write. He can also talk to humans. After a dramatic escape from a mysterious laboratory, Isaiah is separated from his mouse family, and has to use his special skills to survive in the dangerous outdoors, and hopefully find his missing family. But in a world of cruel cats, hungry owls, and terrified people, it's hard for a young, lone mouse to make it alone. When he meets an equally unusual and lonely human girl named Hailey, the two soon learn that true friendship can transcend all barriers.