The famed detective Sherlock faces the possibility of losing his one-of-a-kind deductive skills when he is diagnosed with Post-Concussion Syndrome, a disorder that causes physical and cognitive symptoms including memory loss. With his career, calling, and sobriety all at stake, he must rely even more on his steadfast partner, Dr. Joan Watson. Together, they continue in their mission to crack the NYPD's most baffling crimes and puzzling cases.