Kate has always been a wanderer. A well-published author, married many times, she has lived a life rich with explorations of the natural world and the human soul. Now, at fifty-seven, she leaves her lover, Yolo, to embark on a new excursion, one that begins on the Colorado River, proceeds through the past, and flows, inexorably, into the future. As Yolo begins his own parallel voyage, Kate encounters celibates and lovers, shamans and snakes, memories of family disaster and marital discord, and emerges at a place where nothing remains but love.