Blythe Baxter just moved into a new home above the Littlest Pet Shop. There she meets some unusually talented pets--they can talk! And what's even stranger? Blythe is the only person who can understand them. The pets tell Blythe that the shop is in danger of closing and no one can help but her! Can Blythe save the pets' home or will the shop close its doggie-doors forever.