Virgins in both Ireland and Boston are pregnant, and cities all over the world are being plagued by epidemics, droughts, famines, floods. As Anne Fitzgerald, former-nun-turned-private-investigator, investigates the two women's claims for the Archidiocese of Boston, she becomes aware of danger for all of them -- the future of each of the young women, Anne herself, and the future of all humanity hang on her discovery of the truth.