Tells two stories: the first that of an American company, which starts as a small family soap and candle-making firm in the early 1800s, and ends as a vast pharmaceuticals-to-pesticides combine in the 1990s. The second is that of a contemporary woman, living in the company town, who during the course of the novel is diagnosed and then finally dies of cancer, a cancer that is almost certainly caused by exposure to chemical wastes from the company's factories.