With Manfried the Man as his muse, affable tomcat Steve Catson is finally realizing his dream of becoming a cartoonist. And he's dating Henrietta, a chat noir with a heart of gold. But when a literal fat cat threatens to close down the Catlanta Man Shelter, where stray men get adopted by loving cats, both Steve and Manfried are forced to leave their comfort zone. Steve has to turn lazy Manfried into a prize-winning champion to save the shelter, while Manfried must cope with his new roommate, a young stray man named Garfield.