Being a child prodigy in East Texas can be challenging, but it can also make you the most popular student on your college campus. When 13-year-old undergrad Sheldon Cooper creates a database, his professors clamor for a partnership, but this puts him at odds with the university. Meanwhile, the relationship between his parents, George Sr. and Mary, hits a rough patch, causing his twin sister, Missy, to take off in their dad's truck. Big brother Georgie is thrust headfirst into adulthood when he becomes a father and budding entrepreneur Meemas opens a video store, only to be scrutinized by Pastor Jeff and the entire congregation.