When Uncle Nick is injured trying to come between his pet mouse Mus Mus and Hildy the cat, the other Littles decide to bring some of his old friends, the Trash Tinies, to the house for a surprise. But the journey to Trash City, Uncle Nick's old home, is long and dangerous. Dinky and Della can fly everyone home in their gliders, but getting out of Trash City in one piece is anything but easy. Will the Littles be able to make it home again?