After the death of his half brother, Stefan, at the hands of Vlad Tsepesh--also known as Dracula--and after the destruction of his vampire father, Arkady, also at the hands of Vlad, Abraham van Helsing has traveled the world slaying many vampires. With every vampire he destroys, Bram becomes stronger and Vlad weaker, and soon Bram hopes he will be able to finally kill the fearsome vampire who has kept the Tsepesh family enslaved through a centuries-old blood ritual.