Surrounded by his children, who all seem to be going through life crises involving sex, drugs, and violence; his wife, Karla, who is wrestling with her own demons; and friends like Sonny, who seem to be dying, Duane can't seem to make sense of his life anymore. He gradually makes his way through a protracted end-of-life crisis of which he is finally cured by reading Proust's Remembrance of Things Past, a combination of penance, and prescription from Dr. Carmichael that somehow works.