In the autumn of 1941, Amelia J. McGee, a young woman of Cherokee and Scotch-Irish descent, and an outspoken pamphleteer for the NAACP, hastily sends her daughter, Ella, alone on a bus home to Georgia in the middle of the night-a desperate action that is met with dire consequences when the child encounters two drifters and is left for dead on the side of the road. Ella awakens to find herself in the homestead of Willie Mae Cotton, a wise hoodoo practitioner and former slave, and her partner, Mary-Mary Freeborn, tucked deep in the Takatoka forest. As Ella begins to heal, the legacies of her lineage are revealed.