A gifted but troubled physician, Blue Calhoun runs a thriving medical practice from his Nob Hill mansion in San Francisco while raising his son alone after an unthinkable tragedy. Then one day a female fugitive with a gunshot wound appears in Blue's surgery. Even though she holds a pistol aimed at his heart, the desperation in her eyes awakens Blue's compassion. Reluctantly he is drawn to her fragile beauty, her nerves of steel and the mystery surrounding her circumstances.