When anarchists attack a painting of the Prime Minister and suggest that the man himself could be next, Scotland Yard have no choice but to call in Sherlock Holmes. It is just the start of an adventure that sees Holmes and Watson on the trail of a centures-old puzzle, a puzzle that they are not alone in trying to unravel. As the master cirminal The Albino closes in on them, not to mention the mysterious Lord of Strange deaths, Holmes and Watson find themselves in a race to solve the clues and locate England's long-lost treasure.