The 500 Years of Resistance Comic Book powerfully portrays flashpoints in history when Indigenous peoples have risen up and fought back against colonizers and other oppressors. Events depicted include the the Spanish conquest of the Aztec, Mayan and Inca empires; the 1680 Pueblo Revolt in New Mexico; the Battle of Wounded Knee in 1890; the resistance of the Great Plains peoples in the 19th century; and more recently, the Idle No More protests supporting Indigenous sovereignty and rights in 2012 and 2013, and the resistance to the Dakota Access Pipeline in 2016. Canadian events depicted include the Oka crisis in 1990, the Grand River land dispute between Six Nations and the Government of Canada in 2006, and the Wet'suwet'en anti-pipeline protests in 2020. This revised and expanded edition of The 500 Years of Resistance Comic Book reveals the tenacity and perseverance of Indigenous peoples as they endured 500-plus years of genocide, massacre, torture, rape, displacement, and assimilation: a necessary antidote to conventional histories of the Americas.