Set against the tumultuous political backdrop of late 1960s Chicago, and narrated by 10-year-old Karen Reyes, Monsters is told through a fictional graphic diary employing the iconography of B-movie horror imagery and pulp monster magazines. As the precocious Karen Reyes tries to solve the murder of her beautiful and enigmatic upstairs neighbor, Anka Silverberg, a holocaust survivor, we watch the interconnected and fascinating stories of those around her unfold.