When Smoke Jensen sees a gang of outlaws holding up a stagecoach, he storms in with guns blazing, killing one of the gunmen. The dead man is the brother of the notorious outlaw Gabe Briggs and Briggs will want revenge. Tired of the savagery of the lawless countryside, Smoke's wife Sally heads back east for a spell, only to find the big city choking in filth, violence and corruption. Before Sally can head back home, though, she's snatched right off the street. When Smoke gets word that Sally's been kidnapped, he hops the first train east, but Gabe Briggs and his band of bad men are along for the ride. Unless Smoke can punch their ticket to hell first, they'll low this train sky high...