The FBI's Clarence Otto and CIA agent Drew Phillips comb the country, ruthlessly eliminating people whose minds have been infected by a mysterious disease. The black-ops team is proving a formidable weapon, thanks to the third member of their cadre: one-time football hero Perry Dawsey, now a bloodthirsty psychotic possessed with a strange, valuable new ability. But the biological enemy they are up against is adapting, creating a new breed of infected.