Nearly two decades after the fall, the transcendent city of Iris is the only place rumored to have a cure to the disease that decimated the world. Beyond Iris, are the remnants of the old world, crawling with the Depraved. Infected with Lethe, they no longer remember the people or dreams they were once willing to fight for, and are left instead with familiar voices that whisper dark and unfamiliar words within their minds. Instinct is all that keeps the diseased struggling to exist another day.