Young Fleetwood Shuttleworth is with child again. As the mistress of Gawthorpe Hall, she is anxious to provide her husband with an heir. But none of her previous pregnancies have come to term. Then she discovers a hidden letter from her physician that warns her husband that she will not survive another pregnancy. Distraught over the frightening revelation, Fleetwood wanders the woods of Pendle Hill, where she meets a young local woman named Alice Gray. A midwife, Alice promises Fleetwood she can help her deliver a healthy baby. But soon Alice is drawn into the frenzied accusations of witchcraft sweeping the countryside. Even the woodland creatures, the "familiars," are suspected of practicing the dark arts. Can Fleetwood trust that Alice is really who she says she is?