Leaving behind her private forensic pathology practice in Charleston, South Carolina, Kay Scarpetta accepts an assignment in New York City, where the NYPD has asked her to examine an injured man on Bellevue Hospital's psychiatric prison ward. The handcuffed and chained patient, Oscar Bane, has specifically asked for her, and when she literally has her gloved hands on him, he begins to talk - and the story he has to tell turns out to be one of the most bizarre she has ever heard. The injuries, he says, were sustained in the course of a murder . . . that he did not commit.