The comfortable life of Pickles, the calico housecat, is turned upside down when humans succumb to a zombie apocalypse. She doesn't know where her "pet"--human child Connor--has gone, only that there are zombies everywhere. Determined to find Connor, Pickles sets off with her cat friends and a streetwise raccoon, exploring a world she has only seen through a window. Fending off human zombies, street cats from the wrong side of the track, and a fearsome gang of chipmunks, Pickles and her crew search for remnants of human society.